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Name: glutathione phase 2 detox How The Liver Detoxifies: Glutathione IV for Liver Detox:
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doi: 10.1016/j.scitotenv.2017.12.020 12 GopalakrishnanS.NaiZ.ThilagamH.BeiC.DingJ.WangX

Endoreduplication Duplication of the genome without mitosis, which results in an increase in the nuclear DNA content, permitting amplification of the genome of specialized cells

In addition to Parkin and PINK1 which play a fundamental role in mitophagy, other PD causative genes, including -synuclein, LRRK2 and GBA, may contribute to PD pathogenesis also through their impact on mitophagy which will be discussed below

reported the development of the multifunctional nanosheet system Au/Cu-TCPP(Fe)@RSL3-PEG-iRGD, which triggers ferroptosis in tumor cells by simultaneously blocking the GSH/GPX4 and FSP1/CoQ 10 H 2 pathways via its nanocatalytic activity, as well as synergizing with RSL3 to further inactivate GPX4 in tumor cells